PRAME family member 17 pseudogene (LOC391092 (no recognized gene/protein abbreviation in use for this pseudogene))

PRAME family member 17 pseudogene (LOC391092, ENSG00000223728) is a non-protein-coding segment of DNA related to the PRAME gene family, located in the human genome. As a pseudogene, it is highly homologous to functional PRAME genes but is not transcribed into a functional protein, and thus does not participate in biological pathways, drug interactions, or serve therapeutic roles[1][4][7]. Pseudogenes of the PRAME family arise as disabled genetic copies either through duplication or processing events; their presence in the genome can be used for evolutionary studies, but they do not possess recognized biological function or established relevance in human disease or therapy[7]. Key consideration: Do not use PRAME family member 17 pseudogene (LOC391092, ENSG00000223728) as a therapeutic or diagnostic target. It is a nonfunctional genomic sequence corresponding to a PRAME family paralog. Information about the functional PRAME family members (e.g., PRAMEF17) should not be conflated with this pseudogene, as only the protein-coding forms have biological and disease relevance[3][5].

Other names

PRAME family member 17 pseudogeneLOC391092ENSG00000223728