Pregnancy-specific glycoprotein pseudogene

Pregnancy-specific glycoprotein pseudogene" (ENSG00000269354) refers to a non-functional, processed gene copy within the human pregnancy-specific glycoprotein (PSG) gene cluster on chromosome 19[3][1]. The functional PSGs are secreted proteins involved in immune modulation during pregnancy, but pseudogenes like PSG10 do not encode functional proteins and are generally not studied as therapeutic targets or biomarkers. There are no known functions, disease associations, or interactions for this pseudogene, and it is not considered a drug target or relevant for patient selection or therapeutic monitoring[1][2][3]. - PSG10 is commonly referenced as the main PSG pseudogene in the human gene cluster, which includes PSG1–9 and PSG11 as functional genes, with PSG10 being the only pseudogene described in the cluster[2][3]. - There is evidence of pseudogene transcription, but no indication of functional protein or biological activity[1]. If you are seeking information on functional PSG family targets (e.g., PSG1, PSG7, PSG9), these do have known or emerging roles as biomarkers and in pregnancy immune modulation[2][3], but ENSG00000269354/the PSG pseudogene does not.

Other names

PSG pseudogenePSG10