PRELI domain containing 2 (PRELID2)

PRELI domain containing 2 (PRELID2) is a protein coding gene in humans, predominantly recognized for its predicted function in phosphatidic acid transfer activity and involvement in phospholipid transport within the mitochondrial intermembrane space[4][6]. As a member of the PRELI/MSF1 domain-containing protein family, PRELID2 is evolutionarily conserved and implicated in mitochondrial lipid metabolism, a process crucial for maintaining cellular energy homeostasis and membrane dynamics[2][4]. Functional studies on the PRELI-like family suggest roles in embryogenesis, lymphocyte differentiation, and stress responses, with recent evidence indicating its association with cancer progression, including potential contributions to radiotherapy resistance and tumor microenvironment adaptation[2][6]. No directly approved drugs or therapeutics specifically target PRELID2, although family members are of interest as potential cancer biomarkers and future therapeutic targets.

Other names

PRELI domain-containing protein 2MGC21644FLJ38376CTC-806A22.1