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Target intelligence / Profile preview
PRICKLE1 antisense RNA 1 (PRICKLE1-AS1)
- Target
- PRICKLE1-AS1
- Molecular classification
- long non-coding RNA, antisense RNA
01
Overview
PRICKLE1 antisense RNA 1 (PRICKLE1-AS1) is a non-coding RNA gene transcribed from the antisense strand at or near the PRICKLE1 gene locus. Antisense RNAs are often involved in the regulation of their associated sense transcripts, typically by mechanisms such as transcriptional interference, RNA duplex formation, or influencing chromatin structure. However, for PRICKLE1-AS1, its biological functions, roles in signaling, disease involvement, or utility as a therapeutic target have not yet been established in the scientific literature[9][10]. If you require information on PRICKLE1 itself (the protein-coding gene), substantial evidence supports its functions in cell polarity, Wnt signaling, and neurological development, and it has documented roles in epilepsy and cancer, making it a possible therapeutic target[1][3][5][7]. However, PRICKLE1-AS1 specifically is a non-coding RNA with currently unknown function and no established therapeutic relevance.
- Other names
- PRICKLE1-AS1
02
Mechanism of action
Not established
03
Biological functions
Unknown (likely regulation of gene expression via antisense RNA mechanisms, but no experimentally confirmed functions)
04
Disease associations
Unknown (no robust or widely documented disease associations as of current knowledge)
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