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PRKCZ-DT refers to a divergent or antisense transcript at the PRKCZ gene locus. The "divergent transcript" label generally applies to long noncoding RNAs (lncRNAs) or antisense transcripts that are not translated into functional proteins[4]. PRKCZ itself encodes a serine/threonine kinase known as Protein kinase C zeta (PKCζ), which has broadly characterized roles in cell signaling, differentiation, migration, cancer, and memory[1][2][3][5][6]. However, no literature exists assigning a defined function, structure, or disease relevance to the "PRKCZ-DT" transcript. The term may be used in transcriptome annotations but does not indicate a protein-coding gene, drug target, or therapeutic relevance.
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