Target intelligence / Profile preview

pro-apoptotic WT1 regulator pseudogene 1 (PAWRP1)

Target
PAWRP1
Molecular classification
Other (pseudogene)
01

Overview

Pro-apoptotic WT1 regulator pseudogene 1" (PAWRP1) is a pseudogene, not a protein-coding gene; it is annotated as related to the PAWR (pro-apoptotic WT1 regulator) gene, which encodes the well-characterized tumor suppressor protein Par-4/PAWR[1][4]. PAWRP1 itself is listed without functional annotation in genomic databases[7] and is not described as having protein-coding function, receptor/enzyme/transcription factor activity, or roles in disease or drug interaction. The actual functional target is PAWR, not the pseudogene PAWRP1. Pseudogenes generally do not encode functional proteins and are not considered therapeutic targets. There is no evidence to suggest "PAWRP1" is relevant for targeting, drugs, biomarkers, or safety concerns. If your aim is to refer to an actual therapeutic target, you should use "PRKC apoptosis WT1 regulator protein" (PAWR/Par-4)[1][4]. PAWR is a tumor suppressor regulating apoptosis, but PAWRP1 is not a functional protein. If you need structured data for PAWR (the functional protein), please clarify. For PAWRP1, all target-oriented fields (function, disease, drugs, etc.) should be null since it is not a true target[7].

Other names
PAWRP1PRKCapoptosisWT1regulator pseudogene 1

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