Probable C-mannosyltransferase DPY19L4 (DPY19L4)

DPY19L4 encodes a probable C-mannosyltransferase, an enzyme believed to catalyze the C-mannosylation of tryptophan residues on target proteins, a specific type of glycosylation involved in modulating protein structure and function[1][3][5][7]. The protein is predicted to be a multi-transmembrane protein localized to the endoplasmic reticulum membrane and is part of the evolutionarily conserved DPY19L family[2][7]. While no detailed characterization of DPY19L4 itself currently exists, studies of other DPY19L family members suggest likely involvement in protein glycosylation, cell adhesion, and possibly neuronal development[2]. DPY19L4 is classified as a protein coding gene; mutations in related family members are implicated in human diseases such as male infertility due to globozoospermia, but there is currently limited direct disease or drug-target evidence specific to DPY19L4[7].

Other names

Dpy-19-like protein 4dpy-19 like 4protein dpy-19 homolog 4D19L4hDPY19L4Gm1023LOC203107LOC286148Narg3RGD1305828A0A024R9F2E5RGB7