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Target intelligence / Profile preview
Probable cation-transporting ATPase 13A4 (ATP13A4)
- Target
- ATP13A4
- Molecular classification
- Enzyme, Transporter, Cation transporter, ATPase
01
Overview
Probable cation-transporting ATPase 13A4 (ATP13A4) is a member of the P5 subfamily of P-type ATPases, predicted to function as a **cation-transporting enzyme** using energy from ATP hydrolysis to transport monoatomic cations and polyamines across cellular membranes[4][5]. While its exact physiological function remains incompletely defined, it is believed to play roles in cellular ionic homeostasis and potentially in polyamine transport. ATP13A4 is widely expressed, with RNA present in multiple tissues including the brain[2], and localizes to intracellular membranes[1]. There is currently limited evidence linking ATP13A4 to specific diseases, drug interactions, or use as a biomarker.
- Other names
- ATPase 13A4UNQ3052/PRO9871DKFZp761I1011FLJ37958P5-ATPase isoform 4P5-ATPasecation-transporting P5-ATPaseputative cation-transporting ATPase 13A4ATPase type 13A4
02
Biological functions
ATPase-coupled monoatomic cation transmembrane transporter activityPolyamine transmembrane transporter activityMetal ion transmembrane transport
03
Disease associations
Other (no direct evidence for specific disease association in current results)
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