Probable G protein-coupled receptor 150 (GPR150)

Probable G protein-coupled receptor 150 (GPR150) is an orphan receptor belonging to the large G protein-coupled receptor (GPCR) superfamily, specifically classified within the rhodopsin-like (Class A) GPCRs[1][2]. GPCRs are characterized by their seven-transmembrane helical structure and are crucial for mediating signal transduction in response to various extracellular signals such as hormones, neurotransmitters, and sensory stimuli[1][2]. Although the precise endogenous ligand and physiological role for GPR150 remain currently unknown, the GPCR family as a whole is central to numerous physiological processes and is a major class of drug targets in human healthcare—however, no drugs or ligands are presently known to interact with GPR150 specifically[2]. The lack of detailed functional and pharmacological data reflects its current categorization as an orphan receptor. There are no established disease associations, known biomarkers, or recognized safety considerations unique to GPR150 at this time.

Other names

GPR150PGR11Probable G-protein coupled receptor 150Seven transmembrane helix receptor