Target intelligence / Profile preview

Probable splicing factor YJU2B (YJU2B)

Target
YJU2B
Molecular classification
Splicing factor, Coiled-coil domain protein, Other (not established as receptor, enzyme, transporter, etc.)
01

Overview

YJU2B, also referred to as Probable splicing factor YJU2B or coiled-coil domain-containing protein 130 (CCDC130), is a protein encoded by the human YJU2B gene. It is predicted to participate in RNA splicing processes, particularly as part of the U2-type spliceosomal complex and post-mRNA release spliceosomal complex, located in the nucleus[1][3][7][8]. Functional data suggest it may be involved in mRNA splicing, with potential roles in response to viral infection. Its protein structure includes a coiled-coil domain, but no molecular structure has been experimentally determined[8]. There is no clear evidence to date establishing YJU2B as a direct participant in disease or as a therapeutic target, nor is it a commonly used biomarker for diagnostic or monitoring purposes[3][8].

Other names
YJU2BCCDC130 (Coiled-coil domain-containing protein 130)SB115MGC104719 kDa proteinYJU2 splicing factor homolog BProbable splicing factor YJU2BPutative splicing factor YJU2BCoiled-coil domain containing 130Coiled-coil domain-containing protein 130
02

Biological functions

mRNA splicing (may be involved)RNA splicingComponent of U2-type spliceosomal complex and post-mRNA release spliceosomal complexCellular response to virus
03

Disease associations

Newcastle disease (GeneCards reports it is associated, possibly in research context; not established clinical relevance)Other (no established role as a driver or therapeutic target in specific diseases)

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