Profilin 1 pseudogene 11 (PFN1P11)

Profilin 1 pseudogene 11 (PFN1P11) is a processed pseudogene found in humans, classified within the profilin family. Pseudogenes like PFN1P11 are gene sequences that resemble known protein-coding genes (in this case, the functional PFN1 gene, which encodes the actin-binding protein profilin-1), but they lack the necessary elements to produce functional proteins[3][4]. PFN1P11 does not encode a functional protein and has no established molecular function, clinical role, or direct impact on disease, though its parental gene, PFN1, has well-studied physiological and pathological significance[4][7]. The term "pseudogene" indicates that the sequence is not suitable for direct therapeutic targeting. The essential context is that the functional molecule is "profilin-1" (encoded by PFN1), which is central to actin dynamics and diseases such as ALS and various cancers[1][2][4][5]. PFN1P11, as a pseudogene, should not be mistaken for the functional PFN1 gene product and does not act as a receptor, enzyme, transporter, or any other actionable therapeutic target. If you are seeking information about the actual protein-coding gene with therapeutic and disease relevance, the appropriate target is "Profilin-1 (PFN1)," not PFN1P11.

Other names

PFN1P11