Programmed cell death mechanism (PCD)

Programmed cell death mechanisms are a collection of genetically encoded and actively regulated processes by which cells die in an organized manner. These processes include apoptosis (cell shrinkage, DNA fragmentation), autophagy (self-digestion for cell survival or death), necroptosis and pyroptosis (inflammatory cell death), and ferroptosis (iron-dependent cell death). They play essential roles in development, tissue homeostasis, immune defense, and disease. Dysregulation contributes to a wide array of disorders, such as cancer, neurodegenerative diseases, autoimmune conditions, and infections.

Other names

cell suicideregulated cell deathprogrammed cellular demise