Prohibitin pseudogene 9 (PHB1P9)

PHB1 pseudogene 9 (PHB1P9) is classified as a pseudogene—a segment of DNA related by sequence to the functional PHB1 (prohibitin 1) gene but lacking evidence of coding a functional protein. Pseudogenes such as PHB1P9 are generally considered non-functional remnants that arise during evolution and do not have demonstrated biological or disease-associated roles. All known molecular and therapeutic relevance is related to PHB1, not its pseudogenes. PHB1 is a ubiquitously expressed mitochondrial and nuclear protein with regulatory roles in cell proliferation, apoptosis, signal transduction, and tumor suppression, but PHB1P9 itself is not known to produce protein or participate in these cellular processes. PHB1P9 does not meet classification as a therapeutic target, is considered nonfunctional, and only carries biological relevance by name similarity to PHB1.

Other names

PHB1P9PHBP9prohibitin pseudogene 9

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