Proline dehydrogenase like, pseudogene (PRODHLP)

Proline dehydrogenase like, pseudogene" (PRODHLP) is a human pseudogene located on chromosome 22q11.21[5]. Unlike functional genes, pseudogenes such as PRODHLP do not encode functional proteins and are generally considered inactive genomic remnants. While its nomenclature is similar to the protein-coding gene "Proline dehydrogenase 1" (PRODH), which encodes an important mitochondrial enzyme in proline metabolism and is associated with rare metabolic and neuropsychiatric diseases, PRODHLP itself lacks biological activity and is not implicated in disease, therapy, or drug development[1][5]. This entry is distinct from the related protein-coding "Proline dehydrogenase 1" gene (PRODH), which has known biological functions and disease relevance[2][3][4][6]. PRODHLP is not a therapeutic or research target due to its non-coding, pseudogenic nature[1][5].

Other names

Proline dehydrogenase 1 pseudogenePRODHLP