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Proline-rich and coiled-coil-containing protein 1 (PRRC1) is a human protein encoded by the PRRC1 gene, localized primarily to the Golgi apparatus and cytoplasm[1][2]. The canonical abbreviation is PRRC1. Its biological function is not fully characterized, but it is predicted to regulate protein kinase A (PKA) activity during embryonic development and contribute to epithelial structure maintenance[2][9]. While it has been associated with disorders such as dystonia 23 and congenital contractural arachnodactyly, PRRC1 is not considered a canonical therapeutic target, and there are no known drugs interacting directly with this protein[2]. No safety, biomarker, or mechanism of action information is currently available, reflecting the limited characterization of PRRC1 in biomedical literature[1][2][9].
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