Proline-rich protein 21 pseudogene

Proline-rich protein 21 pseudogene (ENSG00000260610, LOC100419016) is a nonfunctional genomic locus in humans with strong sequence similarity to the functional proline-rich protein 21 (PRR21) gene. Pseudogenes, by definition, are segments of DNA that resemble known genes but contain disabling mutations and generally do not produce a functional protein product. There is no evidence that this pseudogene encodes a protein or has any specific biological function, disease association, or therapeutic relevance. Pseudogenes commonly arise by gene duplication or retrotransposition, and their biological impact is usually limited, although in some cases pseudogenes may contribute to gene regulation through noncoding RNA mechanisms. This entry should not be considered a current or plausible drug target. If you are seeking a functional protein, the relevant entity is likely "Proline-rich protein 21" (PRR21), not the pseudogene. Pseudogenes are frequently annotated in genomic resources, but unless specifically shown to play a regulatory or structural role (such as acting as a non-coding RNA with biological function), they are not classified as molecular targets for drug or biomarker development. No data indicate any role for "proline rich 21 pseudogene" in disease, therapy, or as a marker in clinical contexts. This entry is most accurately classified as incorrect as a drug target because it is not a protein-coding gene, nor is it associated with any defined mechanism or clinical application.

Other names

Proline rich 21 pseudogeneLOC100419016ENSG00000260610