Prolylcarboxypeptidase pseudogene 1 (PRCPP1)

PRCPP1, or prolylcarboxypeptidase pseudogene 1, is a pseudogene related to the functional PRCP gene. The true PRCP gene encodes a lysosomal serine protease that regulates peptides involved in blood pressure and inflammation and is a potential drug target[1][3][4]. However, PRCPP1 itself does not produce a functional protein and is not known to be involved in biological processes, disease, or therapy. A pseudogene is a DNA sequence similar to a known gene but generally nonfunctional due to mutations, truncations, or lack of regulatory elements. Several genomic resources identify PRCPP1 only as a non-coding sequence located on chromosome 2, distinguished from the functional PRCP gene which has clinical and pharmacological relevance[1][3]. PRCPP1 is not cited in databases as a therapeutic target, biomarker, or drug interaction partner. Key clarification: - PRCPP1 is frequently confused with the functional prolylcarboxypeptidase (PRCP), which is an enzyme with biological and therapeutic significance. The search results confirm PRCPP1 is a pseudogene corresponding to PRCP and does not have direct biological functions or therapeutic relevance[1][3].

Other names

PRCPP1prolylcarboxypeptidase (angiotensinase C) pseudogene