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PROSER2 antisense RNA 1 (PROSER2-AS1)
- Target
- PROSER2-AS1
- Molecular classification
- Other (Long non-coding RNA, lncRNA)
01
Overview
PROSER2 antisense RNA 1 (PROSER2-AS1) is a long non-coding RNA (lncRNA) transcribed antisense to the PROSER2 gene. LncRNAs such as PROSER2-AS1 play roles in regulating gene expression at various levels, including transcription and chromatin organization, without encoding proteins[2]. PROSER2-AS1 has been shown to function as a competing endogenous RNA in some cancers, influencing both tumor development and immune cell infiltration by affecting the expression of other RNA molecules and immune-related genes[4]. It is not a therapeutic target such as a receptor, enzyme, or transporter, but rather a molecular biomarker implicated in tumor biology and gene regulation.
- Other names
- PROSER2-AS1
02
Biological functions
Regulation of gene expressionCompeting endogenous RNA (ceRNA) activityModulation of immune cell infiltration
03
Disease associations
Cancer (for example, papillary thyroid carcinoma)Potential biomarker in oncology
04
Biomarkers
Correlates with immune cell biomarkers (such as NOS2, IRF5, PTGS2, CD19, CD79A, HLA-DPB1, etc.) in tumor microenvironment[4]
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