Target intelligence / Profile preview

Prostaglandin E synthase 3 like (PTGES3L)

Target
PTGES3L
Molecular classification
Other
01

Overview

Prostaglandin E synthase 3 like (PTGES3L) is a predicted protein-coding gene in humans, related to the known PTGES3 gene but described as "putative" or "predicted" with no established enzymatic or receptor activity. PTGES3L is thought to enable Hsp90 protein binding and protein-folding chaperone binding activity, potentially being involved in chaperone-mediated protein complex assembly and protein folding, localizing to the cytoplasm, cytosol, and nucleus. There is no clear evidence of it having prostaglandin E synthase enzymatic activity, nor is it recognized as a validated therapeutic target, receptor, enzyme, or transporter[1][4][8][10]. PTGES3L is a putative, unvalidated protein likely involved in chaperone-mediated processes, not an established therapeutic target, with uncertain biological or pharmacological significance.

Other names
Putative protein PTGES3LProstaglandin E synthase 3-likeprostaglandin E synthase 3 (cytosolic)-like
02

Biological functions

Protein foldingChaperone-mediated protein complex assembly
03

Disease associations

Spondylocarpotarsal synostosis syndromeArthrogryposis distal type 1A

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