Prostaglandin E synthase 3 pseudogene 3 (PTGES3P3)

Prostaglandin E synthase 3 pseudogene 3 (PTGES3P3) is a genomic locus annotated as a pseudogene related to prostaglandin E synthase 3. Pseudogenes are DNA sequences that resemble genes but are generally non-functional due to mutations, deletions, or truncations that prevent protein expression. PTGES3P3 does not encode an active enzyme or receptor, and there are no published data indicating a biological function, disease relevance, or drug interactions. It is not considered a therapeutic target or biomarker. The canonical gene/protein "Prostaglandin E synthase 3" (PTGES3) is an active enzyme involved in prostaglandin biosynthesis and may be a therapeutic target, but the "pseudogene 3" version (PTGES3P3) does not encode a functional protein and is not used in research or clinical practice as a target. Including "pseudogene" in the target selection process for drug discovery typically indicates a mistake or misinterpretation of genomic annotation. No aliases, molecular classification, disease associations, or drug interactions are reported for PTGES3P3.