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Target intelligence / Profile preview
Prostate cancer associated transcript 7 (PCAT7)
- Target
- PCAT7
- Molecular classification
- Other, long non-coding RNA (lncRNA)
01
Overview
Prostate cancer associated transcript 7 (PCAT7) is a long non-coding RNA (lncRNA) that is upregulated in metastatic prostate cancer. Knockdown of PCAT7 leads to a substantial decrease in cell growth and anchorage-independent growth, suggesting a role in promoting tumor progression. It has also been implicated in other cancers such as nasopharyngeal carcinoma and cervical cancer. PCAT7 is classified as a non-protein coding RNA and primarily acts at the transcriptional and post-transcriptional regulatory level[1][2][3][4][5][7].
- Other names
- PCAN-R2prostate cancer-associated noncoding RNA 2prostate cancer associated transcript 7 (non-protein coding)
02
Biological functions
Cell proliferationTumor progressionRegulation of gene expression
03
Disease associations
Cancer, specifically Prostate cancerNasopharyngeal carcinomaCervical cancer
04
Biomarkers
Potential biomarker for metastatic prostate cancer progression
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