Proteasome activator subunit 2 pseudogene 2 (PSME2P2)

Proteasome activator subunit 2 pseudogene 2 (PSME2P2) is a processed pseudogene of the human *PSME2* gene, which encodes the beta subunit of the PA28 (11S) proteasome activator complex. While the functional *PSME2* gene product plays a role in immunoproteasome assembly and antigen processing, PSME2P2 lacks the capacity to code for a functional protein due to mutations or sequence truncation. Like other pseudogenes, it may have minor regulatory RNA roles, but is not considered a direct molecular target for drug discovery, receptor research, or therapeutic intervention. Clarification of Issues: - PSME2P2 is a **pseudogene**, not a functional gene or protein, and does not serve as a receptor, enzyme, or drug target in any established context. - Information about protein structure, function, and druggability refers to the *parent gene* (*PSME2*), not to the pseudogene PSME2P2 itself. - If the intent was to find information for the canonical, functional protein, refer to "Proteasome activator subunit 2 (PA28 beta)" (PSME2), *not* to PSME2P2. Summary: PSME2P2 is a non-functional DNA sequence derived from a duplication or retrotransposition of the protein-coding *PSME2* gene. It has no established therapeutic, diagnostic, or pharmacological relevance, and should not be considered a canonical drug target.

Other names

proteasome (prosome, macropain) activator subunit 2 (PA28 beta) pseudogenePSME2 pseudogene 2PA28 beta pseudogene 2