Proteasome subunit alpha 3 pseudogene 1 (PSMA3P1)

Proteasome subunit alpha 3 pseudogene 1 (PSMA3P1) is a human pseudogene related by sequence similarity to the functional gene *proteasome subunit alpha 3 (PSMA3)*, which encodes a protein subunit of the 20S proteasome complex[1][3][7][8]. As a pseudogene, PSMA3P1 does not encode a functional protein, and there is no evidence that it serves as a therapeutic target or is implicated in physiological or pathological processes[5][7]. It is primarily used as a genomic reference and may occasionally be involved in transcriptional regulation, but such functions have not been established for PSMA3P1 specifically.\n\nKey clarifications:\n- PSMA3P1 is a pseudogene, not a protein-coding gene, and does not encode the actual proteasome subunit; therefore, it is not a drug target, and attributes relating to targets (such as drugs, mechanisms, or biomarkers) do not apply[5][7][8].\n- The actual functional target is *Proteasome 20S subunit alpha 3* (gene symbol: PSMA3), not PSMA3P1[2][10].

Other names

PSMA3Pproteasome (prosome, macropain) subunit, alpha type, 3 pseudogene