Proteasome subunit beta 3 pseudogene 1 (PSMB3P1)

PSMB3P1 is a processed pseudogene derived from the parental proteasome subunit beta 3 (PSMB3) gene, located in the human genome, and identified as a retrocopy in primates. While retrocopies like PSMB3P1 can occasionally acquire regulatory roles or neofunctionalization unrelated to their parent genes, the majority—including PSMB3P1—are considered non-functional and do not code for proteins. No evidence supports PSMB3P1 acting as a receptor, enzyme, transporter, or other traditional therapeutic target, nor is it implicated in drug interaction or disease by itself. Functional PSMB3 (not the pseudogene) encodes a core subunit of the 20S proteasome complex, which is central to protein degradation in cells, but the pseudogene PSMB3P1 does not participate in these processes.

Other names

PSMB3Pproteasome (prosome, macropain) subunit, beta type, 3 pseudogeneproteasome subunit beta 3 pseudogene 1