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Protein 50S Ribosomal Subunit (Bacterial) (50S Ribosomal Subunit)
- Target
- 50S Ribosomal Subunit
- Molecular classification
- Ribosomal Subunit, RNA-Protein Complex
01
Overview
The bacterial 50S ribosomal subunit is the larger component of the prokaryotic 70S ribosome, essential for protein synthesis in bacteria. It catalyzes peptide bond formation during translation, provides tRNA binding sites, and is targeted by several antibiotics to inhibit bacterial growth.
- Other names
- Bacterial 50S RibosomeLarge Ribosomal Subunit (Bacterial)50S Ribosomal subunit
02
Mechanism of action
Inhibition of protein synthesis via binding to the 50S ribosomal subunit, blocking peptide bond formation or tRNA translocation.
03
Biological functions
Protein SynthesisPeptidyl Transferase ActivitymRNA Translation
04
Disease associations
Infection
05
Safety considerations
Antibiotic resistanceOff-target effects of antibiotics
06
Interacting drugs
Macrolides
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