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A protein antigen is a molecule, typically a protein or peptide, that can elicit an immune response by being recognized as foreign by the immune system. Protein antigens are highly immunogenic due to their complex structure and multiple epitopes—distinct regions that antibodies or T-cell receptors can recognize and bind. These antigens may be exogenous (originating outside the body), endogenous (produced within cells), or autoantigens (self-proteins targeted in autoimmune diseases).
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