Protein arginine methyltransferase 1 pseudogene 1 (PRMT1P1)

Protein arginine methyltransferase 1 pseudogene 1 (PRMT1P1) is a genomic sequence classified as a pseudogene, meaning it closely resembles the coding gene for protein arginine methyltransferase 1 (PRMT1) but does not produce a functional protein[1][3]. Pseudogenes like PRMT1P1 typically arise from gene duplication or retrotransposition and subsequently accumulate disabling mutations, such as premature stop codons or frameshifts, that result in loss of function[3]. PRMT1P1 may be transcribed at low levels, but its RNA product does not have established functional significance. PRMT1P1 is not a receptor, enzyme, or any other therapeutic target, and current evidence does not ascribe it a clinical role in disease or therapy[3]. If you intended to search for the functional protein arginine methyltransferase 1 (PRMT1), then that is a distinct, functional enzyme with established biological, therapeutic, and disease relevance[2][4]. The name "PRMT1P1" refers specifically to the pseudogene and not to the active enzyme.

Other names

PRMT1 pseudogene 1PRMT1P1

None — mechanism of action information is not applicable to pseudogenes