Protein disulfide isomerase family A member 3 pseudogene 2 (PDIA3P2)

PDIA3P2 is a **pseudogene** related by sequence to the functionally active gene **protein disulfide isomerase family A member 3 (PDIA3)**. PDIA3 itself is an endoplasmic reticulum enzyme involved in catalyzing the formation, breakage, and rearrangement of disulfide bonds during protein folding[1][2][3][4]. However, the "pseudogene" designation for PDIA3P2 indicates it does **not encode a functional protein** and lacks evidence of being a transcribed or translated product with enzymatic or receptor activity. Pseudogenes are generally nonfunctional genomic regions derived from functional genes through evolutionary processes. There is no evidence that PDIA3P2 acts as, or encodes, a **receptor, enzyme, transporter, or therapeutic target**, and it is not catalogued among the 21 functional human PDI family members[4]. PDIA3P2 is not referenced in the context of molecular drug interaction, disease relevance, or experimental targeting in scientific literature. PDIA3P2 is a nonfunctional genomic sequence classified as a pseudogene, not a protein or functional molecular target, and should not be considered a canonical therapeutic target or receptor. If you intended the functional protein (PDIA3), structure data should reference Protein disulfide-isomerase A3 (PDIA3, also called ERp57); if you meant any other member, please clarify.

Other names

PDIA3P2