Protein HEXIM2 (HEXIM2)

Protein HEXIM2 is a transcriptional regulator encoded by the human HEXIM2 gene located on chromosome 17. It acts as a general inhibitor of RNA polymerase II-dependent transcription by being a component of the 7SK small nuclear ribonucleoprotein (snRNP) complex, where it regulates the activity of positive transcription elongation factor b (P-TEFb). HEXIM2 exerts its function by binding to the 7SK snRNA and other protein partners, ultimately modulating transcriptional elongation processes necessary for gene expression. There is no strong evidence supporting HEXIM2 as a direct therapeutic target, nor clear association with disease pathogenesis or known drug interactions based on the currently available information.

Other names

HEXIM P-TEFb complex subunit 2L3FLJ32384Hexamethylene bis-acetamide-inducible protein 2MAQ1 paraloghexamethylene bis-acetamide inducible 2hexamethylene-bis-acetamide-inducible transcript 2