Target intelligence / Profile preview

Protein hinderin

Molecular classification
Other (protein with no known family classification), Structural protein
01

Overview

Protein hinderin (gene symbol KIAA1328) is a human protein that competes with the structural maintenance of chromosomes protein SMC1 for binding to SMC3. This competition may regulate the availability of SMC3 for the assembly of multimeric protein complexes involved in chromosome maintenance and dynamics. The protein is primarily defined by its protein-binding function and does not belong to major molecular families such as receptors, enzymes, ion channels, or transporters. No therapeutic drugs, biomarker uses, or established safety concerns have been identified for this protein, and its precise biological or disease role remains insufficiently characterized.

Other names
KIAA1328hinderinuncharacterized protein KIAA1328KIAA1328 homologexpressed sequence AW554918LOC102554494LOC102724402mKIAA1328RGD1562608RGD1564140
02

Biological functions

Protein-protein interaction (specifically, competes with SMC1 for binding to SMC3 and may regulate formation of multimeric protein complexes)

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