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Protein kinase C eta pseudogene (LOC100419668, ENSG00000259502) is a non-functional genomic sequence closely related to the PRKCH gene, which encodes the active Protein kinase C eta. Pseudogenes are DNA segments that resemble functional genes but typically contain mutations or truncations preventing protein expression. As such, it does not produce a protein, is not involved in canonical signaling pathways, and is not considered a therapeutic target. Confusion can arise with the functional PRKCH gene, which encodes a kinase involved in signal transduction, cell cycle regulation, and cancer, but pseudogenes like LOC100419668 lack these properties[1][3][4].
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