protein kinase cAMP-dependent type I regulatory subunit alpha pseudogene 1 (PRKAR1AP1)

PRKAR1AP1 is classified as a pseudogene—a segment of DNA resembling a gene, but incapable of producing a functional protein product[3][6][8]. It shares high sequence similarity with the functional gene PRKAR1A, which encodes the regulatory subunit type I-alpha of cAMP-dependent protein kinase (Protein Kinase A)[1][7]. However, unlike PRKAR1A, PRKAR1AP1 does not code for a functional protein and lacks a defined biological function or therapeutic application[3][6][8]. Pseudogenes such as PRKAR1AP1 may arise through gene duplication or retrotransposition events but acquire mutations that disrupt protein-coding capacity[6][8]. PRKAR1AP1 should not be considered a drug target, biomarker, or entity with disease association or pharmacological relevance[3][6][8]. This target contains “pseudogene” in its canonical name, and database entries confirm it encodes no protein (amino acid length: 0)[3][6][8]. The functional, clinically relevant gene is PRKAR1A, not PRKAR1AP1[1][7]. No drugs, biomarkers, biological functions, or disease roles are known for PRKAR1AP1.

Other names

PRKAR1APprotein kinase, cAMP-dependent, regulatory subunit type I alpha pseudogeneprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) pseudogeneprotein kinase, cAMP-dependent, regulatory, type I, alpha pseudogenePRKAR1AP1