Target intelligence / Profile preview

Protein KRI1 homolog (KRI1)

Target: KRI1
Molecular classification: Other (Ribosome biogenesis protein, nucleolar protein)

Overview

Protein KRI1 homolog (KRI1) is a nucleolar protein required for the biogenesis of the 40S ribosomal subunit and is involved in the processing of pre-18S ribosomal RNA. It is a member of the KRI1 family, primarily functioning as part of the ribosome assembly machinery, and has been associated with RNA binding activities. Loss-of-function or mutations in KRI1 have been implicated in certain congenital syndromes and malformations, though it is not considered a typical drug target or therapeutic receptor.

Other names: KRI1FLJ12949KRI1 homologprotein KRI1 homolog

Biological functions

Ribosome biogenesisrRNA processingRNA binding

Disease associations

Cerebrocostomandibular syndromeCerebral cavernous malformationsOther (no strong evidence for direct therapeutic targeting)

Beyond the preview

Go deeper on Protein KRI1 homolog (KRI1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Protein KRI1 homolog (KRI1).

Explore the full profile