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A protein macromolecule is a large, complex biological molecule composed of one or more long chains of amino acid residues. Proteins are polymers, meaning they are made up of repeating subunits (monomers), specifically amino acids, linked together by peptide bonds. They are one of the four main classes of biological macromolecules found in all living organisms—the others being carbohydrates, nucleic acids, and lipids. Proteins perform most cellular work and serve an extraordinary range of functions within organisms, including enzymatic catalysis, structural support, transport, signaling, defense mechanisms, and storage. Their function is directly determined by their three-dimensional conformation which arises from their primary sequence.
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