Target intelligence / Profile preview

Protein phosphatase 1 regulatory inhibitor subunit 14B pseudogene 5 (PPP1R14BP5)

Target
PPP1R14BP5
Molecular classification
Other, Pseudogene
01

Overview

Protein phosphatase 1 regulatory inhibitor subunit 14B pseudogene 5 (PPP1R14BP5) is a human pseudogene—a DNA sequence similar to the PPP1R14B gene, but with disabling mutations that prevent it from coding a functional protein. Pseudogenes like PPP1R14BP5 are generally considered non-coding; their primary biological relevance, if any, may be mediated at the RNA level, as some pseudogene transcripts have regulatory functions (such as acting as competing endogenous RNAs or sources of small interfering RNA). There is no evidence that PPP1R14BP5 produces a protein or directly serves as a receptor, enzyme, or other therapeutic target. It is not considered a target in drug discovery or therapy. Note: The inclusion of "pseudogene" in the name and the absence of evidence for a coding or regulatory product marks PPP1R14BP5 as not a therapeutic target and also potentially problematic for inclusion in target catalogs focused on actionable proteins. The query target is formally correct in its naming, but is not valid as a drug target, and inclusion may be a result of data processing error or annotation artifact.

Other names
PPP1R14BP5Protein phosphatase 1, regulatory (inhibitor) subunit 14B pseudogene 5
02

Mechanism of action

None (No drugs target this pseudogene; no mechanism of action established.)

03

Biological functions

No known biological function (as a protein).Pseudogenes generally lack coding capacity, though some can have regulatory RNA-related effects.
04

Disease associations

OtherNo direct pathological role established. Some pseudogenes can influence disease via regulatory RNAs, but no evidence for PPP1R14BP5.

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