Protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 10 (PPP1R2P10)

Protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 10, abbreviated as PPP1R2P10, is a **pseudogene** found in the human genome[7][8]. Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional; most do not produce functional proteins[2]. PPP1R2P10 is one of several processed pseudogenes related to the parental **PPP1R2** gene, which encodes a regulatory subunit for the serine/threonine phosphatase PP1[2]. While the parental PPP1R2 gene product (inhibitor-2) is a well-characterized regulator of protein phosphatase 1 and affects processes such as cell division and neuronal signaling, the PPP1R2P10 sequence itself does not appear to produce a functional protein and is generally classified as non-coding[2][7][8]. Recent research suggests some PPP1R2 pseudogenes may generate RNA transcripts with potential regulatory roles, but PPP1R2P10 specifically is not known to have such a function[2]. This gene is not considered a therapeutic target or relevant for drug interactions, biomarker use, or direct disease associations. **Key clarifications:** - PPP1R2P10 is a pseudogene and **not a protein-coding target** or receptor.[7][8] - The "is_target" field is false because pseudogenes (including PPP1R2P10) are not considered valid drug targets. - The "is_incorrect" field is true because PPP1R2P10 is sometimes incorrectly interpreted as a protein target, though it does not produce a functional protein, and thus does not fit typical definitions of therapeutic targets.

Other names

PPP1R2P10Protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 10[7][8]ENSEMBL: ENSG00000213232[5][8]NCBI Gene: 100128626[7]