Protein phosphatase 1 regulatory subunit 10 pseudogene 1 (PPP1R10P1)

PPP1R10P1 is a pseudogene homologous to protein phosphatase 1 regulatory subunit 10 (PPP1R10/PNUTS). Pseudogenes generally do not encode functional proteins and are not considered therapeutic targets. PPP1R10P1 is likely annotated based on sequence similarity, but no evidence points to its functional protein product or involvement in cellular regulation. The active protein, PPP1R10 (PNUTS), is a nuclear targeting subunit of protein phosphatase 1 (PP1), playing critical roles in cell cycle progression, transcription regulation, chromatin structure, DNA repair, and apoptosis, and is implicated in oncogenesis and neurodegenerative diseases. PPP1R10P1, however, should not be conflated with the active PPP1R10 protein, and references to it as a receptor or target are likely mistaken or incomplete unless new research points to functional relevance[1][2][3][5]. If you want structured information on the canonical target, use PPP1R10 (PNUTS), not PPP1R10P1, for drug targeting, molecular classification, or disease association. The pseudogene does not meet conventional criteria for a therapeutic target.

Other names

PPP1R10P1PPP1R10 pseudogene 1PPP1R10PProtein phosphatase 1, regulatory (inhibitor) subunit 10 pseudogene 1

None for pseudogene