protein phosphatase 1 regulatory subunit 12B pseudogene (PPP1R12B (pseudogene))

Protein phosphatase 1 regulatory subunit 12B pseudogene refers to a non-protein-coding genomic sequence related to PPP1R12B. The functional, protein-coding PPP1R12B gene encodes a key regulatory subunit (MYPT2) of myosin phosphatase, a complex involved in muscle contraction via regulation of myosin light chain phosphorylation. The gene participates in pathways such as beta-adrenergic signaling and cAMP-dependent kinase activation, with specific expression in cardiac, skeletal muscle, and brain. The pseudogene does not produce protein and is generally excluded from drug development and therapeutic targeting[1][3][4][6][7].

Other names

PPP1R12B pseudogeneMYPT2 pseudogeneprotein phosphatase 1, regulatory subunit 12B pseudogenemyosin phosphatase target subunit 2 pseudogene