protein phosphatase 1 regulatory subunit 12B pseudogene 2 (PPP1R12BP2)

Protein phosphatase 1 regulatory subunit 12B pseudogene 2 (PPP1R12BP2) is a **pseudogene**—a DNA sequence related to the protein-coding PPP1R12B gene but lacking evidence of protein-coding function[4][3][8]. The parent gene, PPP1R12B, encodes a regulatory component of myosin phosphatase that participates in muscle contraction by modulating the phosphorylation state of myosin light chains. However, PPP1R12BP2 itself is classified as a pseudogene, meaning it is highly unlikely to be translated into a functional protein and is not considered a receptor, enzyme, transporter, or therapeutic target[4][3][8]. Key distinctions: - **PPP1R12BP2 is not a therapeutic target**; it does not produce an active protein and is not involved in known signaling or disease pathways as a functional unit. - There are no drugs, mechanisms of action, safety concerns, or biomarker roles associated with this pseudogene in human biology. - If you are seeking information about a functional target, you may have intended to query PPP1R12B (myosin phosphatase target subunit 2, MYPT2), which is distinct from the pseudogene and does play a regulatory role in muscle contraction[1][2][6][7]. In summary, **PPP1R12BP2** is a non-functional genetic element and not a valid therapeutic target. If you require information about a protein-coding, functionally relevant target, consider referring to **PPP1R12B** or another related phosphatase regulatory subunit.

Other names

protein phosphatase 1, regulatory (inhibitor) subunit 12B Y-linked pseudogene 2protein phosphatase 1, regulatory (inhibitor) subunit 12B pseudogeneprotein phosphatase 1, regulatory subunit 12B Y-linked pseudogene 2PPP1R12BP2