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Target intelligence / Profile preview
Protein S-Nitrosylation (SNO)
- Target
- SNO
- Molecular classification
- Post-translational modification
01
Overview
Protein S-nitrosylation is a reversible post-translational modification involving the attachment of a nitric oxide (NO) group to cysteine residues, forming S-nitrosothiols (SNOs). This process regulates protein function, conformation, and interactions, influencing various cellular processes and physiological functions. Dysregulation of S-nitrosylation is implicated in several diseases.
- Other names
- S-NitrosylationProtein NitrosylationS-Nitrosothiols formation
02
Biological functions
Signal transductionRegulation of protein activityRegulation of protein conformationRegulation of protein-protein interactionsTranscription regulationDNA repairCell growth and differentiationApoptosisBlood flow autoregulation
03
Disease associations
Neurodegenerative diseasesParkinson's diseaseCardiac tissue dysfunctionSkeletal muscle disordersImmune system abnormalities
04
Safety considerations
Dysregulation leading to disease states
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