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Protein shisa-like-2B (SHISAL2B)
- Target
- SHISAL2B
- Molecular classification
- Other (predicted transmembrane protein, not established as receptor, enzyme, channel, or transporter)
01
Overview
Protein shisa-like-2B (SHISAL2B) is a membrane-associated protein encoded by the SHISAL2B gene in humans. It belongs to the Shisa-like protein family, which are predicted to be transmembrane proteins and may have roles in cellular signaling, likely through indirect regulation, as described in Shisa family members. There is currently no evidence supporting a therapeutic target role for SHISAL2B, nor are there any approved drugs or clear disease biomarker applications. The protein’s precise physiological or pathophysiological function in human tissues remains unclear, although it is expressed in locations like the stomach and pancreatic islets.
- Other names
- Shisa like 2BFAM159Bfamily with sequence similarity 159 member Bmembrane protein FAM159B
02
Biological functions
Other (specific biological function in humans is unclear; generally categorized as a membrane-associated protein; Shisa family proteins may interact with immature forms of the Wnt receptor Frizzled and the FGF receptor in other contexts)
03
Disease associations
Other (associated with abnormality of glucagon secretion and microcystic adenoma; not established as a driver of major disease classes in current data)
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