Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Protein Tyrosine Phosphatase Localized to Mitochondrion 1 (PTPMT1)
- Target
- PTPMT1
- Molecular classification
- Dual-specificity protein tyrosine phosphatase, DSP family, Enzyme, Phosphatase
01
Overview
PTPMT1 is a mitochondrial dual-specificity protein tyrosine phosphatase crucial for cardiolipin biosynthesis. It regulates energy metabolism and has implications in diseases such as mitochondrial dysfunction, diabetes, and cancer. Inhibition of PTPMT1 is being explored as a potential therapeutic strategy.
02
Mechanism of action
Inhibition of PTPMT1 activity
03
Biological functions
Cardiolipin biosynthesisRegulation of energy metabolismRegulation of mitochondrial respirationRegulation of insulin secretionRegulation of apoptosis
04
Disease associations
Mitochondrial dysfunctionMitochondrial Complex II DeficiencyDiabetes mellitusCancer
05
Safety considerations
Disruption of cardiolipin synthesis can lead to mitochondrial dysfunctionPotential impact on normal embryogenesis and development
06
Interacting drugs
Paclitaxel
2 more in the full profile.
Beyond the preview
Go deeper on Protein Tyrosine Phosphatase Localized to Mitochondrion 1 (PTPMT1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Protein Tyrosine Phosphatase Localized to Mitochondrion 1 (PTPMT1).