Protein tyrosine phosphatase pseudogene

This target refers to a *pseudogene* of the protein tyrosine phosphatase family, specifically related to non-receptor type members such as PTPN20C. Pseudogenes arise from duplication or retrotransposition of a parental gene but generally have lost their protein-coding and functional capacities due to accumulating mutations or lack of regulatory elements. Processed pseudogenes, like the one described for PTP4A and related PTPN genes, are formed by retrotransposition and typically lack introns and promoters, reducing their functional relevance in signal transduction or enzyme activity[1][3][4]. Critical Notes: - This entity is *not considered a therapeutic target* because pseudogenes do not encode functional proteins, and there are *no known biological functions, disease roles, drug interactions,* or *mechanisms of action* directly associated with this pseudogene. - The entry is *potentially problematic* for target discovery workflows: It is a pseudogene, not a receptor, enzyme, transporter, or druggable therapeutic target. There is also limited structural or functional annotation available in curated databases for ENSG00000234537, and its inclusion in drug or disease-related studies could be misleading[3][4]. Summary: ENSG00000234537 is a nonfunctional processed pseudogene related to protein tyrosine phosphatases. It is not suitable for therapeutic targeting, biomarker development, or safety assessments, and should not be considered a canonical drug target[1][3][4].

Other names

Protein tyrosine phosphatase, non-receptor type 20C, pseudogenePTPN20C pseudogenePTPN20CPbA164N7.3[4]