Prothymosin alpha pseudogene 1 (PTMAP1)

**Prothymosin alpha pseudogene 1 (PTMAP1)** is a processed pseudogene within the human prothymosin alpha gene family. Unlike the functional prothymosin alpha gene (PTMA), PTMAP1 does not have documented expression evidence nor established protein product, and is considered non-functional. It differs significantly in its coding sequence due to insertions, deletions, and an upstream translation initiation site. Studies analyzing mRNA from human tissues have not found transcripts specific to PTMAP1, supporting its classification as a pseudogene with no known biological activity or therapeutic target potential[1][4][9]. **Key interpretation notes:** - PTMAP1 is not a protein-coding gene and is classified as a pseudogene, not a receptor, enzyme, or any conventional drug target[1][9]. - The functional gene of interest for prothymosin alpha biology is PTMA, not PTMAP1. All known biological functions, clinical significance, and therapeutic interactions are attributed to PTMA or its protein product, prothymosin alpha—not this pseudogene[3][5][6]. - No drug interactions, disease roles, or molecular mechanisms are associated with PTMAP1, consistent with its pseudogene classification[1][9].

Other names

Em:AB023049.6PTMAP1