Drug pipeline
Explore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Proto-oncogene tyrosine-protein kinase Src (SRC)
- Target
- SRC
- Molecular classification
- Non-receptor tyrosine kinase, Enzyme
01
Overview
Proto-oncogene tyrosine-protein kinase Src (SRC) is a non-receptor tyrosine kinase that plays a central role in multiple cellular processes, including cell growth, development, and signal transduction. It is involved in pathways downstream of integrins and interacts with receptor tyrosine kinases, G-protein-coupled receptors, and steroid receptors. Aberrant SRC function is associated with cancer progression.
- Other names
- c-Srcp60src
02
Mechanism of action
Kinase inhibitor
03
Biological functions
Regulation of embryonic developmentCell growth regulationSignal transductionPhosphorylation of proteinsCell adhesionCell migrationCell proliferationCell differentiationCell survivalCell motilityAngiogenesisCytoskeletal organizationPre-mRNA processing
04
Disease associations
CancerColorectal CancerThrombocytopenia 6
05
Safety considerations
Potential for off-target effects due to the involvement of SRC in multiple cellular processes
Beyond the preview
Go deeper on Proto-oncogene tyrosine-protein kinase Src (SRC).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Follow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Compare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Investigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Explore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Connect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Proto-oncogene tyrosine-protein kinase Src (SRC).