Target intelligence / Profile preview

Protocadherin beta 17 pseudogene (PCDHB17P)

Target
PCDHB17P
Molecular classification
Other (Pseudogene; member of cadherin superfamily—specifically, protocadherin beta cluster)
01

Overview

Protocadherin beta 17 pseudogene (PCDHB17P) is a genomic sequence classified as a pseudogene, meaning it closely resembles a protein-coding gene but is not believed to produce a functional protein in humans[6]. As part of the clustered protocadherin beta family, it is related to the cadherin superfamily, key for cell adhesion and neural development, but PCDHB17P itself is not known to encode a functional cell adhesion protein due to mutations or deletions that disrupt its coding potential[6][7]. No evidence indicates that PCDHB17P acts as a receptor, functional protein, or regulatory RNA of therapeutic significance[6][7]. It is cataloged at chromosome location 5:141155999-141158409 and may be mentioned in breast cancer association studies, but causation or biological function has not been established[6]. There are no drugs, mechanisms, biomarkers, or safety issues relevant to clinical targeting. Pseudogenes like PCDHB17P are generally not considered therapeutic targets.

Other names
ME4PCDH-psi1PCDHB17
02

Disease associations

Breast cancer (association noted; not demonstrated as functional disease gene)

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