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Provision of metabolizable glucose describes the physiological processes that ensure glucose is available in a form that can be metabolized by cells to produce energy. This encompasses dietary glucose absorption, hepatic glucose output via gluconeogenesis or glycogenolysis, transport into the bloodstream, and cellular uptake using specific glucose transporters (notably GLUT4 in muscle and adipose tissue)[2][1][3][5][6]. The processes are regulated by hormones such as insulin and glucagon, but "provision of metabolizable glucose" itself is not a molecular entity or singular drug target, and thus is not suitable for direct annotation as a target[2][6].
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