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PRR11 antisense RNA 1 (PRR11-AS1)
- Target
- PRR11-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Other
01
Overview
PRR11 antisense RNA 1 (PRR11-AS1) is a long non-coding RNA (lncRNA) gene located on human chromosome 17, known primarily for its regulatory role in gene expression, especially at the PRR11 locus[3][4][5]. It is also referred to as AC099850.3, AC099850.4, lnc-SKA2-1, and CTD-2510F5.4. PRR11-AS1 is associated with certain cancers, including lung cancer and hepatocellular carcinoma, where its altered expression correlates with tumor cell proliferation and invasion[3][6]. No small-molecule drugs or approved therapeutic agents target PRR11-AS1 directly, and it is not currently considered a canonical therapeutic target such as a receptor, enzyme, or transporter. Its main categorization is as a regulatory lncRNA, and it serves as a candidate for cancer research, but not as a direct drug target[3][5][6].
- Other names
- AC099850.3AC099850.4lnc-SKA2-1CTD-2510F5.4
02
Biological functions
Regulation of gene expressionModulation of cell proliferationModulation of cell invasion
03
Disease associations
Cancer (notably lung cancer, hepatocellular carcinoma)Other (potential but not fully established for other conditions)
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