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PRSS23 antisense RNA 1 (PRSS23-AS1)

Target: PRSS23-AS1
Molecular classification: Long non-coding RNA, Other (for mechanistic roles as ceRNA)

Overview

PRSS23 antisense RNA 1 (PRSS23-AS1) is a long non-coding RNA transcribed in the opposite direction of the PRSS23 gene. It functions as a competing endogenous RNA (ceRNA) and is implicated in breast cancer, where increased expression of PRSS23-AS1 promotes cell proliferation, invasion, and metastasis. Mechanistically, it may sequester specific microRNAs, indirectly regulating target gene expression. Currently, PRSS23-AS1 is being studied for its role in cancer biology, but it is not considered a direct therapeutic target or receptor, nor is it associated with approved drugs or clinical safety concerns[2].

Other names: Lnc-PRSS23-AS1

Biological functions

Acts as a competing endogenous RNA (ceRNA)May regulate gene expression by modulating microRNA activity

Disease associations

Cancer (specifically implicated in breast cancer)

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