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Pseudogene similar to killer cell lectin-like receptor subfamily C, member 1

Molecular classification
Other (Pseudogene)
01

Overview

ENSG00000249305 encodes a **pseudogene** highly similar in sequence to "killer cell lectin-like receptor subfamily C, member 1" (KLRC1), but does not produce a functional protein product and is not regarded as biologically active in humans[5]. Therefore, it is not considered a therapeutic or diagnostic target. Functional members of the killer cell lectin-like receptor family, such as the KLRC or KLRA subfamilies, are involved in immune regulation, particularly in natural killer (NK) cells, but their pseudogenes do not participate in these processes[2][5][6]. **Key clarification:** - This entry is a **pseudogene**—it may be included in gene lists or outputs from computational searches, but it should *not* be considered an active target or receptor. - The confusion stems from similarity to receptor gene names; "similar to killer cell lectin-like receptor subfamily C, member 1" merely describes sequence homology and does not imply function. If you need information about **functional** killer cell lectin-like receptors (such as KLRC1 or KLRA1), these are actual proteins involved in **immune cell signaling** and bear relevance as immune cell receptors[2][4][7]. For this specific entry, there are no asserted biological functions, no known active protein, and no clinical drug associations.

Other names
Pseudogene similar to KLRC1

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